A self-interference canceller (SIC) is incorporated into a transceiver to reduce or eliminate modem jamming when a transmitter in the transceiver transmits at high power levels. The SIC is configured to receive at a first input a transmitter noise reference signal including a self-interfering signal component generated by the transmitter, to receive at a second input a corrupted signal including the self-interfering signal component and a desired signal component generated by the transmitter, and to output a correction signal that resembles the self-interfering signal component. The correction signal is subtracted from the corrupted signal to generate a processed signal that is input to the modem. The SIC may be disabled when the output power of the transmitter is at a level below a predetermined threshold. The invention may be applied to a multi-radio access technology (RAT) transceiver.