A method for managing clinical study (CS) information for a clinical research entity using a server system coupled to a centralized database and at least one client system is provided. The centralized database has a plurality of templates stored therein. The method includes receiving at the server system CS information relating to at least one patient involved in a clinical study wherein the CS information is entered through a user selected template displayed on the client system, storing CS information received at the server system in the centralized database, tracking CS information stored in the centralized database, updating the centralized database periodically with newly received CS information to maintain CS information, and providing CS information in response to an inquiry.