Invention Grant
US07871616B2 Anti-IL-22RA antibodies and binding partners and methods of using in inflammation
有权
抗IL-22RA抗体和结合配偶体以及在炎症中使用的方法
- Patent Title: Anti-IL-22RA antibodies and binding partners and methods of using in inflammation
- Patent Title (中): 抗IL-22RA抗体和结合配偶体以及在炎症中使用的方法
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Application No.: US12540084Application Date: 2009-08-12
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Publication No.: US07871616B2Publication Date: 2011-01-18
- Inventor: Wenfeng Xu , Wayne R. Kindsvogel , Yasmin A. Chandrasekher , Stacey R. Dillon , Joyce M. Lehner , Anthony W. Siadak , Pallavur V. Sivakumar , Margaret Dow Moore
- Applicant: Wenfeng Xu , Wayne R. Kindsvogel , Yasmin A. Chandrasekher , Stacey R. Dillon , Joyce M. Lehner , Anthony W. Siadak , Pallavur V. Sivakumar , Margaret Dow Moore
- Applicant Address: US WA Seattle
- Assignee: ZymoGenetics, Inc.
- Current Assignee: ZymoGenetics, Inc.
- Current Assignee Address: US WA Seattle
- Agent Nicholas V. Sherbina
- Main IPC: A61K39/395
- IPC: A61K39/395
Abstract:
The present invention relates to blocking, inhibiting, reducing, antagonizing or neutralizing the activity of IL-22, IL-20, or both IL-20 and IL-22 polypeptide molecules. IL-20 and IL-22 are cytokines that are involved in inflammatory processes and human disease. IL-22RA (zcytor11) is a common receptor for IL-20 and IL-22. The present invention includes anti-IL-22RA antibodies and binding partners, as well as methods for antagonizing IL-22 or both IL-20 and IL-22 using such antibodies and binding partners.
Public/Granted literature
- US20100210825A1 ANTI-IL-22RA ANTIBODIES AND BINDING PARTNERS AND METHODS OF USING IN INFLAMMATION Public/Granted day:2010-08-19
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