Invention Grant
- Patent Title: Composition having antitumor effect
- Patent Title (中): 具有抗肿瘤作用的组合物
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Application No.: US10594443Application Date: 2005-03-31
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Publication No.: US07871765B2Publication Date: 2011-01-18
- Inventor: Hitoshi Kotani , Yasufumi Kaneda , Hirokazu Kawano , Masayuki Fukumura , Masayuki Kurooka
- Applicant: Hitoshi Kotani , Yasufumi Kaneda , Hirokazu Kawano , Masayuki Fukumura , Masayuki Kurooka
- Applicant Address: JP Osaka JP Osaka
- Assignee: GenomIdea Inc.,AnGesMG, Inc.
- Current Assignee: GenomIdea Inc.,AnGesMG, Inc.
- Current Assignee Address: JP Osaka JP Osaka
- Agency: Banner & Witcoff, Ltd.
- Priority: JP2004-108599 20040331; JP2004-136756 20040430; JP2005-044639 20050221
- International Application: PCT/JP2005/006820 WO 20050331
- International Announcement: WO2005/094878 WO 20051013
- Main IPC: C12Q1/70
- IPC: C12Q1/70

Abstract:
The present invention is intended to provide a pharmaceutical composition for delivering a chemotherapeutic, preferably an anticancer drug, into cells or into a living organism, using a viral envelope vector, and provides a pharmaceutical composition comprising a chemotherapeutic encapsulated in, or used in combination with, a viral envelope vector having an adjuvanticity as an active ingredient. Thereby it is possible to introduce an anticancer drug encapsulated in a viral envelope vector directly into a tumor, with coadministration of another anticancer drug so as to induce tumor cell-specific antitumor immunity also thanks to the adjuvant action of HVJ-E, and hence to regress the tumor. The present invention also provides a pharmaceutical composition comprising a viral envelope vector and a chemotherapeutic as active ingredients.
Public/Granted literature
- US20080226674A1 Composition Having Antitumor Effect Public/Granted day:2008-09-18
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