Invention Grant
- Patent Title: Methylated CpG polynucleotide
- Patent Title (中): 甲基化CpG多核苷酸
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Application No.: US10553948Application Date: 2004-04-23
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Publication No.: US07871984B2Publication Date: 2011-01-18
- Inventor: Yukio Sato , Hiroko Kobayashi
- Applicant: Yukio Sato , Hiroko Kobayashi
- Applicant Address: JP Fukushima JP Tokyo
- Assignee: Yukio Sato,Taisho Pharmaceutical Co., Ltd.
- Current Assignee: Yukio Sato,Taisho Pharmaceutical Co., Ltd.
- Current Assignee Address: JP Fukushima JP Tokyo
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: JP2003-118999 20030423
- International Application: PCT/JP2004/005935 WO 20040423
- International Announcement: WO2004/094448 WO 20041104
- Main IPC: A01N43/04
- IPC: A01N43/04
Abstract:
It is an object of the present invention to provide a polynucleotide, which can effectively suppress the immunoreactivity caused by DNA having a CpG motif and which can be used for preventing and/or treating immune-mediated diseases such as arthritis. The present invention provides a polynucleotide comprising a CpG motif wherein guanine is methylated, and a pharmaceutical composition comprising the above-mentioned polynucleotide.
Public/Granted literature
- US20080200407A1 Methylated cpg polynucleotide Public/Granted day:2008-08-21
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