Invention Grant
US07872111B2 Process for producing protein with reduction of acidic sugar chain and glycoprotein produced thereby
有权
生产蛋白质的方法是由此产生的酸性糖链和糖蛋白的还原
- Patent Title: Process for producing protein with reduction of acidic sugar chain and glycoprotein produced thereby
- Patent Title (中): 生产蛋白质的方法是由此产生的酸性糖链和糖蛋白的还原
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Application No.: US12184334Application Date: 2008-08-01
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Publication No.: US07872111B2Publication Date: 2011-01-18
- Inventor: Masami Miura , Masaaki Hirose , Taeko Miwa , Hiroyuki Irie , Shinobu Kuwae , Kenmi Miyano , Wataru Otani , Hideyuki Ohi
- Applicant: Masami Miura , Masaaki Hirose , Taeko Miwa , Hiroyuki Irie , Shinobu Kuwae , Kenmi Miyano , Wataru Otani , Hideyuki Ohi
- Applicant Address: JP Osaka
- Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee: Mitsubishi Tanabe Pharma Corporation
- Current Assignee Address: JP Osaka
- Agency: Kilyk & Bowersox, P.L.L.C.
- Priority: JP2000-144643 20000517
- Main IPC: C07H21/04
- IPC: C07H21/04 ; C12N1/00 ; C12N14/39 ; C12N9/10
Abstract:
A protein participating in the addition of mannose phosphate to a sugar chain of a glycoprotein originating in a yeast belonging to the genus Pichia; a gene coding this protein; a mutant of this gene; a vector carrying the mutant gene; a yeast strain belonging to the genus Pichia having been transformed by this vector; a process for producing a protein with reduction of an acidic sugar chain by using the transformed yeast strain; and a glycoprotein thus produced, are described.
Public/Granted literature
- US20090004725A1 Process For Producing Protein With Reduction of Acidic Sugar Chain and Glycoprotein Produced Thereby Public/Granted day:2009-01-01
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