Invention Grant
- Patent Title: Expression vector encoding apoptosis-specific eIF-5A
- Patent Title (中): 编码凋亡特异性eIF-5A的表达载体
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Application No.: US11595990Application Date: 2006-11-13
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Publication No.: US07872112B2Publication Date: 2011-01-18
- Inventor: Catherine A. Taylor , Tzann-Wei Wang , Larry Petrov , John C. Carlson , Richard Narayansingh , Marianne Kaup , Dominic Cliche , John E. Thompson
- Applicant: Catherine A. Taylor , Tzann-Wei Wang , Larry Petrov , John C. Carlson , Richard Narayansingh , Marianne Kaup , Dominic Cliche , John E. Thompson
- Applicant Address: US NJ New Brunswick
- Assignee: Senesco Technologies, Inc.
- Current Assignee: Senesco Technologies, Inc.
- Current Assignee Address: US NJ New Brunswick
- Agency: Morgan, Lewis & Bockius LLP
- Main IPC: C07H21/04
- IPC: C07H21/04
Abstract:
The present invention relates to isolated and/or purified rat apoptosis-specific eucaryotic initiation Factor-5A (eIF-5A) and deoxyhypusine synthase (DHS) nucleic acids and polypeptides. The present invention also relates to methods of modulating apoptosis using apoptosis-specific eIF-5A and DHS, and antisense oligonucleotides and expression vectors of apoptosis-specific eIF-5A and DHS useful in such methods.
Public/Granted literature
- US20070059831A1 Nucleic acids, polypeptides, compositions, and methods for modulating apoptosis Public/Granted day:2007-03-15
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