Invention Grant
US07872134B2 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates
失效
2 - {[2-(取代氨基)乙基]磺酰基}乙基N,N-双(2-氯乙基)磷酰胺
- Patent Title: 2-{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates
- Patent Title (中): 2 - {[2-(取代氨基)乙基]磺酰基}乙基N,N-双(2-氯乙基)磷酰胺
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Application No.: US11955177Application Date: 2007-12-12
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Publication No.: US07872134B2Publication Date: 2011-01-18
- Inventor: Edgardo Laborde , Andrew B. Kelson , Wenli Ma , Kevin T. Weber
- Applicant: Edgardo Laborde , Andrew B. Kelson , Wenli Ma , Kevin T. Weber
- Applicant Address: US CA Palo Alto
- Assignee: Telik, Inc.
- Current Assignee: Telik, Inc.
- Current Assignee Address: US CA Palo Alto
- Agency: Foley & Lardner LLP
- Main IPC: C07F9/572
- IPC: C07F9/572 ; C07F9/576 ; C07F9/24 ; A61K31/664 ; A61K31/675
![2-{[2-(substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates](/abs-image/US/2011/01/18/US07872134B2/abs.jpg.150x150.jpg)
Abstract:
2-{[2-(Substituted amino)ethyl]sulfonyl}ethyl N,N-bis(2-chloroethyl)phosphorodiamidates and their salts, their preparation and intermediates in their preparation, pharmaceutical compositions containing them, and methods of treatment using them. The compounds are useful for treating cancer and autoimmune diseases, alone and in combination with other therapies.
Public/Granted literature
- US20090156559A1 2-ethyl N,N-bis(2-chloroethyl)phosphorodiamidates Public/Granted day:2009-06-18
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