Invention Grant
- Patent Title: Saccharide-measuring fluorescent monomer, saccharide-measuring fluorescent sensor substance, and implantable, saccharide-measuring sensor
- Patent Title (中): 糖测量荧光单体,糖测荧光传感器物质和可植入的糖测量传感器
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Application No.: US12222579Application Date: 2008-08-12
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Publication No.: US07873398B2Publication Date: 2011-01-18
- Inventor: Shouji Ochiai , Tetsuro Kawanishi , Atsushi Matsumoto
- Applicant: Shouji Ochiai , Tetsuro Kawanishi , Atsushi Matsumoto
- Applicant Address: JP Shibuya-Ku, Tokyo
- Assignee: Terumo Kabushiki Kaisha
- Current Assignee: Terumo Kabushiki Kaisha
- Current Assignee Address: JP Shibuya-Ku, Tokyo
- Agency: Buchanan Ingersoll & Rooney PC
- Priority: JP2004-216535 20040723; JP2004-299991 20041014
- Main IPC: A61B5/00
- IPC: A61B5/00

Abstract:
A saccharide-measuring fluorescence sensor substance including a copolymer of at least the following two compounds (I) and (II) is provided: (I) a fluorescent monomer compound represented by the following formula (1): formula (1) wherein: Q, Q′ and D3 may be the same or different, may be combined together into a fused ring, and are each a substituent selected from the group consisting of a hydrogen atom, a halogen atom, a hydroxyl group, and substituted or unsubstituted alkyl, acyl, oxyalkyl, carboxyl, carboxylate ester, carboxamido, cyano, nitro, amino and aminoalkyl groups; and D1, D2 and D4 each represent a substituent, wherein at least one of D1, D2 and D4 is a substituent group comprising a vinyl group at an end thereof, and wherein the substituent group comprising a vinyl group at an end thereof enables the fluorescent monomer compound to be soluble in water, and (II) at least one hydrophilic, polymerizable monomer having a vinyl group.
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