Invention Grant
US07875705B2 Tumor diagnostic agent used in PET comprising anti-ROBO1 antibody
有权
用于含有抗ROBO1抗体的PET的肿瘤诊断剂
- Patent Title: Tumor diagnostic agent used in PET comprising anti-ROBO1 antibody
- Patent Title (中): 用于含有抗ROBO1抗体的PET的肿瘤诊断剂
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Application No.: US11946220Application Date: 2007-11-28
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Publication No.: US07875705B2Publication Date: 2011-01-25
- Inventor: Hiroko Iwanari , Isao Kohno , Takao Hamakubo , Yoshitaka Kumakura , Hirotaka Itoh , Toshiko Sakihama , Hiroyuki Aburatani , Toshimitsu Momose
- Applicant: Hiroko Iwanari , Isao Kohno , Takao Hamakubo , Yoshitaka Kumakura , Hirotaka Itoh , Toshiko Sakihama , Hiroyuki Aburatani , Toshimitsu Momose
- Applicant Address: JP Tokyo JP Tokyo
- Assignee: The University of Tokyo,Perseus Proteomics Inc.
- Current Assignee: The University of Tokyo,Perseus Proteomics Inc.
- Current Assignee Address: JP Tokyo JP Tokyo
- Agency: Greenblum & Bernstein, P.L.C.
- Priority: JP2007-140356 20070528
- Main IPC: C07K16/00
- IPC: C07K16/00
Abstract:
It is an object of the present invention to provide a novel antibody capable of specifically recognizing ROBO1 that is expressed in a cell membrane, a hybridoma that produces the above antibody, a method for producing the above antibody, and a tumor diagnostic agent used in PET comprising the above antibody. The present invention provides a monoclonal antibody capable of specifically recognizing ROBO1 existing on the surface of a cell, which is obtained by immunizing an animal to be immunized with a ROBO1-displaying budded baculovirus recovered from the culture supernatant of host cells infected with a recombinant baculovirus comprising the full-length cDNA of ROBO1 as an antigen.
Public/Granted literature
- US20090092544A1 Tumor diagnostic agent used in PET comprising anti-ROBO1 antibody Public/Granted day:2009-04-09
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