Some embodiments of an infusion pump system can incorporate an accelerometer or other motion sensor to detect the user's activity level. If the user's activity level indicates that he or she is exercising or otherwise at an elevated level, the infusion pump device can be configured to automatically adjust the dispensation rate of a medicine such as insulin. Accordingly, an insulin delivery rate can be corrected to account for a user's activity level (e.g., an elevated activity level during exercise or the like).