Invention Grant
US07879317B2 Polymeric micelle compositions with improved stability and methods of making thereof
有权
具有改进的稳定性的聚合胶束组合物及其制备方法
- Patent Title: Polymeric micelle compositions with improved stability and methods of making thereof
- Patent Title (中): 具有改进的稳定性的聚合胶束组合物及其制备方法
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Application No.: US10493043Application Date: 2002-10-17
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Publication No.: US07879317B2Publication Date: 2011-02-01
- Inventor: Min-Hyo Seo , Sa-Won Lee , Hee-Jo Kim , Jeong-Kyung Kim , Myung-Han Huyn , Jeong-il Yu , Bong-Oh Kim
- Applicant: Min-Hyo Seo , Sa-Won Lee , Hee-Jo Kim , Jeong-Kyung Kim , Myung-Han Huyn , Jeong-il Yu , Bong-Oh Kim
- Applicant Address: KR Seoul
- Assignee: Samyang Corporation
- Current Assignee: Samyang Corporation
- Current Assignee Address: KR Seoul
- Agency: Birch, Stewart, Kolasch & Birch, LLP
- Priority: KR2001-64468 20011018; KR2001-76213 20011204
- International Application: PCT/KR02/01942 WO 20021017
- International Announcement: WO03/033592 WO 20030424
- Main IPC: A61K8/72
- IPC: A61K8/72 ; A61K31/74
Abstract:
Polymeric compositions capable of forming stable micelles in an aqueous solution, comprising an amphiphilic block copolymer of a hydrophilic block and a hydrophobic block, and a polylactic acid derivative wherein one end of the polylactic acid is covalently bound to at least one carboxyl group. The carboxyl group of the polylactic acid derivative may be fixed with a di- or tri-valent metal ion, obtained by adding the di- or tri-valent metal ion to the polymeric composition.
Public/Granted literature
- US20040253195A1 Polymeric michelle composition with improved stability Public/Granted day:2004-12-16
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