Invention Grant
- Patent Title: Recombinant antibodies for treatment of respiratory syncytial virus infections
- Patent Title (中): 用于治疗呼吸道合胞病毒感染的重组抗体
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Application No.: US12073538Application Date: 2008-03-06
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Publication No.: US07879329B2Publication Date: 2011-02-01
- Inventor: Johan Lantto , Henriette Schjønning Nielsen
- Applicant: Johan Lantto , Henriette Schjønning Nielsen
- Applicant Address: DK Lyngby
- Assignee: Symphogen A/S
- Current Assignee: Symphogen A/S
- Current Assignee Address: DK Lyngby
- Agency: Sterne, Kessler, Goldstein & Fox P.L.L.C.
- Priority: DK200701291 20070907
- Main IPC: A61K39/42
- IPC: A61K39/42 ; A61K39/155

Abstract:
Disclosed are novel polyclonal antibodies, which target respiratory syncytial virus (RSV), as well as novel high affinity antibody molecules reactive with RSV. The polyclonal antibodies may comprise antibody molecules which are reactive with both RSV protein F and RSV protein G, and preferably the polyclonal antibodies target a variety of epitopes on these proteins. The antibody molecules of the invention have shown superior efficacy in vitro and/or in vivo. Also disclosed are methods of producing the antibodies of the invention as well as methods of their use in treatment or prevention of RSV infection.
Public/Granted literature
- US20080226630A1 Recombinant antibodies for treatment of respiratory syncytial virus infections Public/Granted day:2008-09-18
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