Invention Grant
- Patent Title: Antibodies against type A botulinum neurotoxin
- Patent Title (中): A型肉毒杆菌神经毒素抗体
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Application No.: US11368727Application Date: 2006-03-06
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Publication No.: US07879330B2Publication Date: 2011-02-01
- Inventor: Sina Bavari , Edna R. Torres Melendez , Frank J. Lebeda
- Applicant: Sina Bavari , Edna R. Torres Melendez , Frank J. Lebeda
- Applicant Address: US DC Washington
- Assignee: The United States of America as represemted by the Secretary of the Army
- Current Assignee: The United States of America as represemted by the Secretary of the Army
- Current Assignee Address: US DC Washington
- Agent Elizabeth Arwine
- Main IPC: G01N33/554
- IPC: G01N33/554 ; C07H21/04 ; C12P21/06 ; C07K16/12

Abstract:
Antibodies for binding epitopes of BoNT/A and hybridomas which produce such antibodies are described. The antibodies of the present invention can be used in a method for detecting BoNT/A in a sample and/or in a method for purifying BoNT/A from an impure solution. In addition, the antibodies can be used for passive immunization against BoNT/A intoxication or as intoxication therapy. Another aspect of the invention is a kit for detecting BoNT/A in a sample.
Public/Granted literature
- US20060177881A1 Antibodies against type A botulinum neurotoxin Public/Granted day:2006-08-10
Information query
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