Invention Grant
- Patent Title: Mutant porcine reproductive and respiratory syndrome virus
- Patent Title (中): 突变型猪繁殖与呼吸综合征病毒
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Application No.: US11718828Application Date: 2005-11-02
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Publication No.: US07879337B2Publication Date: 2011-02-01
- Inventor: Dongwan Yoo , Changhee Lee , Jay Gregory Calvert
- Applicant: Dongwan Yoo , Changhee Lee , Jay Gregory Calvert
- Applicant Address: US NJ Madison
- Assignee: Pfizer Inc.
- Current Assignee: Pfizer Inc.
- Current Assignee Address: US NJ Madison
- Agent Brandon Boss; E. Victor Donahue
- International Application: PCT/IB2005/003366 WO 20051102
- International Announcement: WO2006/051396 WO 20060518
- Main IPC: A61K39/12
- IPC: A61K39/12 ; A61K31/7088 ; C12N7/00 ; C12N7/02 ; C12N7/04 ; C12N5/10 ; C12N15/40
Abstract:
The present invention provides a genetically modified PRRS virus which has been modified such that the conserved cysteine in the E protein has been deleted or changed to a non-cysteine residue and polynucleotides that encode it. Vaccines comprising the genetically modified virus and polynucleotides are also provided.
Public/Granted literature
- US20090004221A1 Mutant Porcine Reproductive and Respiratory Syndrome Virus Public/Granted day:2009-01-01
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