Invention Grant
- Patent Title: Method of detecting mutations associated with thrombosis
- Patent Title (中): 检测与血栓形成相关的突变的方法
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Application No.: US10579584Application Date: 2004-11-17
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Publication No.: US07879543B2Publication Date: 2011-02-01
- Inventor: Susan Bortolin , Frank Merante , Daniel Kobler , Daniel Fieldhouse , Margot Boszko , Hemanshu Modi , Richard A. Janeczko , Roman Zastawny
- Applicant: Susan Bortolin , Frank Merante , Daniel Kobler , Daniel Fieldhouse , Margot Boszko , Hemanshu Modi , Richard A. Janeczko , Roman Zastawny
- Applicant Address: CA Toronto
- Assignee: Luminex Molecular Diagnostics, Inc.
- Current Assignee: Luminex Molecular Diagnostics, Inc.
- Current Assignee Address: CA Toronto
- Agency: Goodwin Procter LLP
- International Application: PCT/CA2004/001974 WO 20041117
- International Announcement: WO2005/047533 WO 20050526
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; C12P19/34 ; C07H21/04
Abstract:
The present invention provides a method for the simultaneous identification of two or more single base changes in a plurality of target nucleotide sequences that are markers associated with cardiovascular diseases such as deep vein thrombosis and the like. Multiplex detection is accomplished using multiplexed tagged allele specific primer extension (ASPE) and hybridization of such extended primers to a probe, preferably an addressable anti-tagged support.
Public/Granted literature
- US20070160992A1 Method of detecting mutations associated with thrombosis Public/Granted day:2007-07-12
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