Invention Grant
- Patent Title: Modulators that promote cell surface expression of odorant receptors
- Patent Title (中): 促进气味受体细胞表面表达的调节剂
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Application No.: US12207102Application Date: 2008-09-09
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Publication No.: US07879565B2Publication Date: 2011-02-01
- Inventor: Hiroaki Matsunami , Momoka Matsunami , Harumi Saito , Hanyi Zhuang
- Applicant: Hiroaki Matsunami , Momoka Matsunami , Harumi Saito , Hanyi Zhuang
- Applicant Address: US NC Durham
- Assignee: Duke University
- Current Assignee: Duke University
- Current Assignee Address: US NC Durham
- Agency: Casimir Jones SC
- Main IPC: G01N33/566
- IPC: G01N33/566 ; C07K14/705
Abstract:
The present invention relates to polypeptides capable of promoting odorant receptor cell surface localization and odorant receptor functional expression. The present invention further provides assays for the detection of ligands specific for various odorant receptors. Additionally, the present invention provides methods of screening for odorant receptor accessory protein polymorphisms and mutations associated with disease states, as well as methods of screening for therapeutic agents, ligands, and modulators of such proteins.
Public/Granted literature
- US20090092997A1 MODULATORS THAT PROMOTE CELL SURFACE EXPRESSION OF ODORANT RECEPTORS Public/Granted day:2009-04-09
Information query
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