Invention Grant
US07879792B2 Synthetic peptide inhibitors of thrombin and thrombin activation of protease activated receptors 1 and 4
失效
凝血酶的合成肽抑制剂和蛋白酶活化的受体1和4的凝血酶活化
- Patent Title: Synthetic peptide inhibitors of thrombin and thrombin activation of protease activated receptors 1 and 4
- Patent Title (中): 凝血酶的合成肽抑制剂和蛋白酶活化的受体1和4的凝血酶活化
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Application No.: US11142364Application Date: 2005-06-02
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Publication No.: US07879792B2Publication Date: 2011-02-01
- Inventor: Alvin H. Schmaier , Henry I. Mosberg , Fernanda F. Marques , John Hilfinger
- Applicant: Alvin H. Schmaier , Henry I. Mosberg , Fernanda F. Marques , John Hilfinger
- Applicant Address: US MI Ann Arbor
- Assignee: The Regents of the University of Michigan
- Current Assignee: The Regents of the University of Michigan
- Current Assignee Address: US MI Ann Arbor
- Agency: Marshall, Gerstein & Borun LLP
- Main IPC: A61K38/00
- IPC: A61K38/00 ; A61K38/04 ; A61K38/36
Abstract:
The invention relates to synthetic peptide analogs of D-Arg-Oic-Pro-Gly-Phe and methods of their use to inhibit human platelet aggregation, thrombosis and cell activation mediated by PAR1 and PAR4.
Public/Granted literature
- US20060276402A1 Synthetic peptide inhibitors of thrombin and thrombin activation of protease activated receptors 1 and 4 Public/Granted day:2006-12-07
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