Invention Grant
- Patent Title: Compositions comprising cell-impermeant duramycin derivatives
- Patent Title (中): 包含细胞不渗透的耐久霉素衍生物的组合物
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Application No.: US10642059Application Date: 2003-08-15
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Publication No.: US07879801B2Publication Date: 2011-02-01
- Inventor: Philip E. Thorpe , Jin He
- Applicant: Philip E. Thorpe , Jin He
- Applicant Address: US TX Austin
- Assignee: Board of Regents, The University of Texas System
- Current Assignee: Board of Regents, The University of Texas System
- Current Assignee Address: US TX Austin
- Agent Shelley P. M. Fussey
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
Disclosed are surprising discoveries concerning the role of anionic phospholipids and aminophospholipids in tumor vasculature and in viral entry and spread, and compositions and methods for utilizing these findings in the treatment of cancer and viral infections. Also disclosed are advantageous antibody, immunoconjugate and duramycin-based compositions and combinations that bind and inhibit anionic phospholipids and aminophospholipids, for use in the safe and effective treatment of cancer, viral infections and related diseases.
Public/Granted literature
- US20040147440A1 Compositions comprising cell-impermeant duramycin derivatives Public/Granted day:2004-07-29
Information query
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