Invention Grant
US07879816B2 Methods of treating cancer and other conditions or disease states using LFMAU and LDT
有权
使用LFMAU和LDT治疗癌症和其他病症或疾病状态的方法
- Patent Title: Methods of treating cancer and other conditions or disease states using LFMAU and LDT
- Patent Title (中): 使用LFMAU和LDT治疗癌症和其他病症或疾病状态的方法
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Application No.: US11921194Application Date: 2006-06-05
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Publication No.: US07879816B2Publication Date: 2011-02-01
- Inventor: Yung-chi Cheng
- Applicant: Yung-chi Cheng
- Applicant Address: US CT New Haven
- Assignee: Yale University
- Current Assignee: Yale University
- Current Assignee Address: US CT New Haven
- Agent Henry D. Coleman; R. Neil Sudol; William J. Sapone
- International Application: PCT/US2006/021742 WO 20060605
- International Announcement: WO2006/133092 WO 20061214
- Main IPC: A01N43/04
- IPC: A01N43/04 ; A61K31/70

Abstract:
The present invention relates to the use of the compound according to formula (I), below for the treatment of tumors, cancer and hyperproliferative diseases, among other conditions or disease states: Where X is H or F; R1 and R2 are independently H, an acyl group, a C1-C20 alkyl or ether group, a phosphate, diphosphate, triphosphate or a phosphodiester group, a (A) or (B) group; Where Nu is a radical of a biologically active compound such as an anticancer, antiviral or antihyperproliferative compound such that an amino group or hydroxyl group from said biologically active agent forms a phosphate, phosphoramidate, carbonate or urethane group with the adjacent moiety; each R8 is independently H, or a C1-C20 alkyl or ether group, preferably a C1-C12 alkyl group; k is 0-12, preferably, 0-2; and pharmaceutically acceptable salts thereof.
Public/Granted literature
- US20080292687A1 Methods of Treating Cancer and Other Conditions or Disease States Using Lfmau and Ldt Public/Granted day:2008-11-27
Information query
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