Invention Grant
- Patent Title: Serine hydrolase inhibitors
- Patent Title (中): 丝氨酸水解酶抑制剂
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Application No.: US11903483Application Date: 2007-09-20
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Publication No.: US07879846B2Publication Date: 2011-02-01
- Inventor: Kevin Shreder , Yi Hu , Allister Fraser , Yasushi Kohno , Akihiko Kojima , Junichi Ishiyama
- Applicant: Kevin Shreder , Yi Hu , Allister Fraser , Yasushi Kohno , Akihiko Kojima , Junichi Ishiyama
- Applicant Address: JP Tokyo
- Assignee: Kyorin Pharmaceutical Co.., Ltd.
- Current Assignee: Kyorin Pharmaceutical Co.., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Jones Day
- Main IPC: C07D413/04
- IPC: C07D413/04 ; A61K31/536
Abstract:
Provided herein are benzoxazinone compounds of formula I and compositions containing the compounds. The compounds and compositions are useful in the methods of inhibiting the action of serine hydrolase, including neutrophil elastase. In certain embodiments, the compounds and compositions are useful in the prevention, amelioration or treatment of serine hydrolase-mediated diseases.
Public/Granted literature
- US20080161290A1 Serine hydrolase inhibitors Public/Granted day:2008-07-03
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