Invention Grant
- Patent Title: Diagnosis and treatment of type 2 diabetes and other disorders
- Patent Title (中): 诊断和治疗2型糖尿病等疾病
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Application No.: US11664381Application Date: 2006-11-17
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Publication No.: US07879859B2Publication Date: 2011-02-01
- Inventor: Yun-Ping Zhou , Jing Li , Weizhen Wu , Jin Shang , John R. Thompson , Nancy A. Thornberry
- Applicant: Yun-Ping Zhou , Jing Li , Weizhen Wu , Jin Shang , John R. Thompson , Nancy A. Thornberry
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Baerbel R. Brown; Kenrick L. Vidale; John C. Todaro
- International Application: PCT/US2006/044939 WO 20061117
- Main IPC: A61K31/50
- IPC: A61K31/50 ; A61K31/496 ; A61K31/44 ; A61K31/415 ; A61K31/40
Abstract:
The present application features the use of the somatostatin subtype 3 receptor (SST3) as a target for affecting insulin secretion and for diagnosing diabetes related disorders. Glucose stimulated insulin secretion was found to be stimulated by knocking down expression of SST3 and through the use of a SST3 selective antagonist.
Public/Granted literature
- US20090131451A1 Diagnosis and treatment of type 2 diabetes and other disorders Public/Granted day:2009-05-21
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