Invention Grant
- Patent Title: Crystalline antifungal compounds
- Patent Title (中): 结晶抗真菌化合物
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Application No.: US11882892Application Date: 2007-08-06
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Publication No.: US07879867B2Publication Date: 2011-02-01
- Inventor: Antonio Cánovas Paredes , Javier Bartroli Orpi , Elies Molins Grau , Anna Roig Serra , Kevin Meyer , Keith Lorimer
- Applicant: Antonio Cánovas Paredes , Javier Bartroli Orpi , Elies Molins Grau , Anna Roig Serra , Kevin Meyer , Keith Lorimer
- Applicant Address: ES Palau-solita i Plegamans US FL Coral Gables
- Assignee: Palau Pharma, S.A.,Stiefel Laboratories, Inc.
- Current Assignee: Palau Pharma, S.A.,Stiefel Laboratories, Inc.
- Current Assignee Address: ES Palau-solita i Plegamans US FL Coral Gables
- Agent Gary M. Nath; Joshua B. Goldberg; Charles D. Niebylski
- Priority: EP06380225 20060807; EP07380186 20070626
- Main IPC: A61K31/517
- IPC: A61K31/517

Abstract:
Novel crystalline forms of (1R,2R)-7-chloro-3-[2-(2,4-difluorophenyl)-2 -hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin-4(3H)-one, pharmaceutical compositions containing these crystalline forms, methods of using these crystalline forms for treating and/or preventing various microbial and/or fungal infections or disorders, and processes for obtaining these crystalline forms. In particular, the present subject matter relates to the specific crystalline Forms I, II, III, IV, V, and VI of (1R,2R)-7-chloro-3-[2 -(2,4-difluorophenyl)-2-hydroxy-1-methyl-3-(1H-1,2,4-triazol-1-yl)propyl]quinazolin -4(3H)-one, represented by formula II:
Public/Granted literature
- US20080076787A1 Crystalline antifungal compounds Public/Granted day:2008-03-27
Information query
IPC分类: