Invention Grant
US07880001B2 Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
有权
11-β-羟基类固醇脱氢酶1型酶的抑制剂
- Patent Title: Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme
- Patent Title (中): 11-β-羟基类固醇脱氢酶1型酶的抑制剂
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Application No.: US11119022Application Date: 2005-04-29
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Publication No.: US07880001B2Publication Date: 2011-02-01
- Inventor: James T. Link , Yixian Chen , Hwan-Soo Jae , Jyoti R. Patel , Marina A. Pliushchev , Jeffrey J. Rohde , Qi Shuai , Bryan K. Sorensen , Martin Winn , Dariusz Wodka , Hong Yong
- Applicant: James T. Link , Yixian Chen , Hwan-Soo Jae , Jyoti R. Patel , Marina A. Pliushchev , Jeffrey J. Rohde , Qi Shuai , Bryan K. Sorensen , Martin Winn , Dariusz Wodka , Hong Yong
- Applicant Address: US IL Abbott Park
- Assignee: Abbott Laboratories
- Current Assignee: Abbott Laboratories
- Current Assignee Address: US IL Abbott Park
- Agent Sreenivasarao Vepachedu
- Main IPC: A61K31/496
- IPC: A61K31/496 ; C07D401/04
Abstract:
The present invention relates to compounds which are inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme. The present invention further relates to the use of inhibitors of 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme for the treatment of non-insulin dependent type 2 diabetes, insulin resistance, obesity, lipid disorders, metabolic syndrome, and other diseases and conditions that are mediated by excessive glucocorticoid action.
Public/Granted literature
- US20050277647A1 Inhibitors of the 11-beta-hydroxysteroid dehydrogenase Type 1 enzyme Public/Granted day:2005-12-15
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