A wireless system suitable for use as a radio frequency (RF) locationing or presence detection system includes at least one wireless access device and at least wireless device, such as an active RF tag, corresponding to an item or asset of interest. A method of managing RF transmissions by the wireless devices is provided. The method involves the wireless device receiving keep-alive beacons during a first period of time. During this first period of time, the wireless device is operated in a transmit mode. During a second period of time that follows the first period of time, the wireless device receives no keep-alive beacons. During this second period of time, the wireless device is operated in a standby mode such that RF transmissions are disabled.