A method using various heuristics techniques for resolving ambiguity in location determination in environments with or without noise. A final location determination solution may be determined from a set of ambiguous location determination solutions by using clock temporal bias value, by using consistency information of ranging signal order such as the time of arrival and/or the received power level of the ranging signals, by using the distances to the sources, and/or by using other discriminator functions to select the final location determination solution from a plurality of ambiguous location determination solutions. The main advantage of the heuristic approaches is that redundant measurements are not required for location determination solution disambiguation.