Techniques for simulating universal serial bus (USB) video devices are described. In one example, a document containing a USB video device descriptor set is loaded by a device simulator application. The document is parsed and the descriptor set is extracted. The descriptor set is then used to define a simulated USB video device. A device simulation framework simulates a USB device attachment to a computing device and video data is streamed from the simulated USB video device to the computing device. A video driver associated with the computing device processes the video data as if the data originated from USB video device hardware. Multiple different USB video devices may be simulated and different collections and configurations of video data can be utilized.