A method of optimizing clock-gated circuitry in an integrated circuit (IC) design is provided. A plurality of signals which feed into enable inputs of a plurality of clock gates is determined, where the clock gates gate a plurality of sequential elements in the IC design. Combinational logic which is shared among the plurality of signals is identified. The clock-gated circuitry is transformed into multiple levels of clock-gating circuitry based on the shared combinational logic.