A system and method for a symbiotic computer application and system and method for generation and presentation of same. The symbiotic computer application allows end-user devices to access back-end data systems including legacy host data systems having legacy host applications and other alternative data systems not directly compatible with the end-user devices. In some embodiments, the symbiotic computer application is generated by a symbiotic computer application generator to include user interface forms and discrete associations, which relate the user interface forms to the back-end data systems. A symbiotic computer application presentation end-user system allows the end-user device to perform desired functions of the back-end data systems through programs and user interfaces configured for the end-user device.