Invention Grant
- Patent Title: Isolation and preservation of fetal hematopoietic and mesencymal system cells from non-controversial materials and/or tissues resulting from miscarriages and methods of therapeutic use
- Patent Title (中): 从流产引起的非争议性材料和/或组织和治疗用途的方法分离和保存胎儿造血和间歇系统细胞
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Application No.: US11654737Application Date: 2007-01-17
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Publication No.: US07883698B2Publication Date: 2011-02-08
- Inventor: Maria Michejda
- Applicant: Maria Michejda
- Agent Rashida A. Karmali
- Main IPC: A01N63/00
- IPC: A01N63/00 ; A01N1/02
Abstract:
The present invention is directed to compositions of fetal hematopoietic stem and progenitor cells and stromal (mesencymal) cells derived from second trimester (16-20 weeks gestation) miscarriages, that are isolated, processed and cryopreserved, and the therapeutic uses of such stem and progenitor cells upon application. Such compositions may be useful for hematopoietic reconstitution and/or replacement in patients with various diseases and metabolic disorders. The invention also relates to methods for collecting, isolating, processing and cryopreserving of the fetal stem and progenitor cells of the invention. Importantly, the invention meets an urgent need in regenerative medicine while at the same time ensures utility of the product compositions because it utilizes fetal materials from second trimester (16-20 weeks of gestation) spontaneously lost pregnancies which are free of moral or ethical burdens.
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