Invention Grant
- Patent Title: Ketoreductase polypeptides for the production of azetidinone
- Patent Title (中): 用于产生氮杂环丁酮的酮还原酶多肽
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Application No.: US12243968Application Date: 2008-10-01
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Publication No.: US07883879B2Publication Date: 2011-02-08
- Inventor: Onorato Campopiano , Emily Mundorff , Birthe Borup , Rama Voladri
- Applicant: Onorato Campopiano , Emily Mundorff , Birthe Borup , Rama Voladri
- Applicant Address: US CA Redwood City
- Assignee: Codexis, Inc.
- Current Assignee: Codexis, Inc.
- Current Assignee Address: US CA Redwood City
- Main IPC: C12N9/00
- IPC: C12N9/00 ; C12N9/04 ; C12Q1/26 ; C12P7/62 ; C12P17/10 ; C07H21/04
Abstract:
The present disclosure provides engineered ketoreductase enzymes having improved properties as compared to a naturally occurring wild-type ketoreductase enzyme. Also provided are polynucleotides encoding the engineered ketoreductase enzymes, host cells capable of expressing the engineered ketoreductase enzymes, and methods of using the engineered ketoreductase enzymes to synthesize a variety of chiral compounds.
Public/Granted literature
- US20090162909A1 Ketoreductase Polypeptides for the Production of Azetidinone Public/Granted day:2009-06-25
Information query
