Invention Grant
- Patent Title: Compounds for the treatment of proliferative disorders
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Application No.: US11355922Application Date: 2006-02-16
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Publication No.: US07884094B2Publication Date: 2011-02-08
- Inventor: Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- Applicant: Lijun Sun , Christopher Borella , Hao Li , Jun Jiang , Shoujun Chen , Keizo Koya , Takayo Inoue , Zhenjian Du , Kevin Foley , Yaming Wu , Mei Zhang , Weiwen Ying
- Applicant Address: US MA Lexington
- Assignee: Synta Pharmaceuticals Corp.
- Current Assignee: Synta Pharmaceuticals Corp.
- Current Assignee Address: US MA Lexington
- Agency: Foley & Lardner LLP
- Agent Steven G. Davis
- Main IPC: A61K31/33
- IPC: A61K31/33 ; C07D261/02

Abstract:
The invention relates to compounds of structural formula (I): or a pharmaceutically acceptable salt, solvate, clathrate, and prodrug thereof, wherein Ra, Rb, and R2 are defined herein. These compounds inhibit tubulin polymerization and/or target vasculature and are useful for treating proliferative disorders, such as cancer.
Public/Granted literature
- US20060217389A1 Compounds for the treatment of proliferative disorders Public/Granted day:2006-09-28
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