Invention Grant
- Patent Title: Anthranilamide inhibitors of aurora kinase
- Patent Title (中): 邻氨基苯甲酰胺抑制剂极光激酶
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Application No.: US12524009Application Date: 2008-01-25
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Publication No.: US07884098B2Publication Date: 2011-02-08
- Inventor: Jeffrey Michael Axten , Deborah L. Bryan , David Harold Drewry , Thomas H Faitg , Timothy Francis Gallagher , Neil W Johnson , Jiri Kasparec , Jeffrey M Ralph , Domingos J. Silva
- Applicant: Jeffrey Michael Axten , Deborah L. Bryan , David Harold Drewry , Thomas H Faitg , Timothy Francis Gallagher , Neil W Johnson , Jiri Kasparec , Jeffrey M Ralph , Domingos J. Silva
- Applicant Address: US PA Philadelphia
- Assignee: GlaxoSmithKline LLC
- Current Assignee: GlaxoSmithKline LLC
- Current Assignee Address: US PA Philadelphia
- Agent Robert H. Brink
- International Application: PCT/US2008/051985 WO 20080125
- International Announcement: WO2008/092049 WO 20080731
- Main IPC: A61K31/5355
- IPC: A61K31/5355 ; A61K31/541 ; A61K31/505 ; A61K31/506 ; C07D279/12 ; C07D403/02 ; C07D239/24 ; C07D413/02
Abstract:
The present invention relates to a compound represented by the following formula: or a pharmaceutically acceptable salt thereof; wherein R1, R1′ R2, R3, R4, R5, r and s are as defined herein. Compounds of the present invention are useful in the treatment of diseases associated with Aurora kinase activity such as cancer.
Public/Granted literature
- US20100016318A1 ANTHRANILAMIDE INHIBITORS OF AURORA KINASE Public/Granted day:2010-01-21
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