Invention Grant
US07884104B2 Aminopiperidines as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
有权
氨基哌啶作为二肽基肽酶-IV抑制剂用于治疗或预防糖尿病
- Patent Title: Aminopiperidines as dipeptidyl peptidase-IV inhibitors for the treatment or prevention of diabetes
- Patent Title (中): 氨基哌啶作为二肽基肽酶-IV抑制剂用于治疗或预防糖尿病
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Application No.: US11662064Application Date: 2005-09-27
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Publication No.: US07884104B2Publication Date: 2011-02-08
- Inventor: Jason M. Cox , Scott D. Edmondson , Bart Harper , Ann E. Weber
- Applicant: Jason M. Cox , Scott D. Edmondson , Bart Harper , Ann E. Weber
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme Corp.
- Current Assignee: Merck Sharp & Dohme Corp.
- Current Assignee Address: US NJ Rahway
- Agent Janet E. Fair; John C. Todaro
- International Application: PCT/US2005/034775 WO 20050927
- International Announcement: WO2006/039325 WO 20060413
- Main IPC: A61K31/4545
- IPC: A61K31/4545 ; C07D487/04
Abstract:
The present invention is directed to novel substituted aminopiperidines which are inhibitors of the dipeptidyl peptidase-IV enzyme (“DPP-IV inhibitors”) and which are useful in the treatment or prevention of diseases in which the dipeptidyl peptidase-IV enzyme is involved, such as diabetes and particularly Type 2 diabetes. The invention is also directed to pharmaceutical compositions comprising these compounds and the use of these compounds and compositions in the prevention or treatment of such diseases in which the dipeptidyl peptidase-IV enzyme is involved.
Public/Granted literature
- US20080076773A1 Aminopiperidines as Dipeptidyl Peptidase-IV Inhibitors for the Treatment or Prevention of Diabetes Public/Granted day:2008-03-27
Information query
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