Invention Grant
US07884110B2 Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation
有权
稠合杂芳基吡啶基和苯基苯磺酰胺作为CCR2调节剂用于治疗炎症
- Patent Title: Fused heteroaryl pyridyl and phenyl benzenesuflonamides as CCR2 modulators for the treatment of inflammation
- Patent Title (中): 稠合杂芳基吡啶基和苯基苯磺酰胺作为CCR2调节剂用于治疗炎症
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Application No.: US12171782Application Date: 2008-07-11
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Publication No.: US07884110B2Publication Date: 2011-02-08
- Inventor: Antoni Krasinski , Sreenivas Punna , Solomon Ungashe , Qiang Wang , Yibin Zeng
- Applicant: Antoni Krasinski , Sreenivas Punna , Solomon Ungashe , Qiang Wang , Yibin Zeng
- Applicant Address: US CA Mountain View
- Assignee: ChemoCentryx, Inc.
- Current Assignee: ChemoCentryx, Inc.
- Current Assignee Address: US CA Mountain View
- Agency: Brinks Hofer Gilson & Lione
- Main IPC: A01N43/90
- IPC: A01N43/90 ; A61K31/52 ; A61K31/519 ; C07D473/00 ; C07D487/00

Abstract:
Compounds are provided that act as potent antagonists of the CCR2 receptor. The compounds are generally aryl sulfonamide derivatives and are useful in pharmaceutical compositions, methods for the treatment of CCR2-mediated diseases and as controls in assays for the identification of CCR2 antagonists.
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