Invention Grant
US07884179B2 Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
有权
核酸和相应的标题为STEAP-1的蛋白质可用于治疗和检测癌症
- Patent Title: Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer
- Patent Title (中): 核酸和相应的标题为STEAP-1的蛋白质可用于治疗和检测癌症
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Application No.: US11581227Application Date: 2006-10-12
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Publication No.: US07884179B2Publication Date: 2011-02-08
- Inventor: Mary Faris , Wangmao Ge , Arthur B. Raitano , Pia M. Challita-Eid , Aya Jakobovits
- Applicant: Mary Faris , Wangmao Ge , Arthur B. Raitano , Pia M. Challita-Eid , Aya Jakobovits
- Applicant Address: US CA Santa Monica
- Assignee: Agensys, Inc.
- Current Assignee: Agensys, Inc.
- Current Assignee Address: US CA Santa Monica
- Agent Mark T. Kresnak; Shane M. Popp; Ginger R. Dreger
- Main IPC: A61K38/00
- IPC: A61K38/00
Abstract:
A novel gene 08P1D4 (also designated STEAP-1) and its encoded protein, and variants thereof, are described wherein STEAP-1 exhibits tissue specific expression in normal adult tissue, and is aberrantly expressed in the cancers listed in Table I. Consequently, STEAP-1 provides a diagnostic, prognostic, prophylactic and/or therapeutic target for cancer. The STEAP-1 gene or fragment thereof, or its encoded protein, or variants thereof, or a fragment thereof, can be used to elicit a humoral or cellular immune response; antibodies or T cells reactive with STEAP-1 can be used in active or passive immunization.
Public/Granted literature
- US20090169476A1 Nucleic acid and corresponding protein entitled STEAP-1 useful in treatment and detection of cancer Public/Granted day:2009-07-02
Information query
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