Invention Grant
- Patent Title: Synthetic agonists of TLR9
- Patent Title (中): TLR9的合成激动剂
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Application No.: US11954726Application Date: 2007-12-12
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Publication No.: US07884197B2Publication Date: 2011-02-08
- Inventor: Ekambar Kandimalla , Mallikarjuna Putta , Dong Yu , Lakshmi Bhagat , Daqing Wang , Sudhir Agrawal
- Applicant: Ekambar Kandimalla , Mallikarjuna Putta , Dong Yu , Lakshmi Bhagat , Daqing Wang , Sudhir Agrawal
- Applicant Address: US MA Cambridge
- Assignee: Idera Pharmaceuticals, Inc.
- Current Assignee: Idera Pharmaceuticals, Inc.
- Current Assignee Address: US MA Cambridge
- Agency: Preti Flaherty
- Agent Wayne A. Keown
- Main IPC: C07H21/02
- IPC: C07H21/02 ; C07H21/04 ; C12Q1/68 ; C12N5/00 ; C12N5/02 ; A61K49/00 ; A61K31/70 ; A01N43/04
Abstract:
The invention provides novel oligonucleotide-based compounds that individually provide distinct immune response profiles through their interactions as agonists with TLR9. The TLR9 agonists according to the invention are characterized by specific and unique chemical modifications, which provide their distinctive immune response activation profiles.
Public/Granted literature
- US20080292648A1 SYNTHETIC AGONISTS OF TLR9 Public/Granted day:2008-11-27
Information query
