In a wireless system, a method and system for channel estimation in a single channel MIMO system comprising two-transmit and multiple-receive antennas for WCDMA/HSDPA are provided. A first receive antenna and at least one additional receive antenna may receive a plurality of SC communication signals transmitted from a first and an additional transmit antennas. Estimates of the propagation channels between transmit and receive antennas may be performed concurrently and may be determined from a baseband combined channel estimate. The integration time may be based on channel estimation accuracy and wireless modem performance. The signals received in the additional receive antennas may be multiplied by a rotation waveform to achieve channel orthogonality. The rotation waveform's amplitude and phase components may be modified based on the channel estimates. Rotation of the received signals in the additional receive antennas may be continuous or periodic.