A package pickup indicator system is disclosed. The system includes a monitoring system and an indicator capable of being detected by a route driver for a shipping carrier in a shipping carrier vehicle. The monitoring system is in communication with at least one shipping carrier customer package tracking system and is in communication with the indicator. The monitoring system is configured to activate the indicator when a package at a place of business is ready to be picked up for shipment by the shipping carrier and is further configured to query the shipping carrier customer package tracking system about a status of the package to be shipped. The monitoring system automatically deactivates the indicator upon a response from the shipping carrier customer package system that the package to be shipped is in possession of the shipping carrier.