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Invention Grant
US07887835B2 Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound 有权
包含氟取代的烷基的化合物和包含该化合物的脂质体造影剂

  • Patent Title: Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound
  • Patent Title (中): 包含氟取代的烷基的化合物和包含该化合物的脂质体造影剂
  • Application No.: US11898968
    Application Date: 2007-09-18
  • Publication No.: US07887835B2
    Publication Date: 2011-02-15
  • Inventor: Kazunobu Takahashi , Kazuhiro Aikawa
  • Applicant: Kazunobu Takahashi , Kazuhiro Aikawa
  • Applicant Address: JP Tokyo
  • Assignee: FUJIFILM Corporation
  • Current Assignee: FUJIFILM Corporation
  • Current Assignee Address: JP Tokyo
  • Agency: Sughrue Mion, PLLC
  • Priority: JP2006-252510 20060919; JP2006-252511 20060919; JP2006-254062 20060920; JP2006-267249 20060929; JP2007-083543 20070328
  • Main IPC: A61K9/127
  • IPC: A61K9/127
Compound comprising a fluorine-substituted alkyl group and a liposome contrast medium comprising the compound
Abstract:
A steroid ester compound of a terminally-fluorinated alkyl fatty acid, a steroid compound having bis(trifluoromethyl)phenyl group, a phosphatidylserine compound having a terminally-fluorinated alkyl group, a glyceride compound having bis(trifluoromethyl phenyl group, or a glyceride compound having a terminally-fluorinated alkyl group. A vascular lesion can be selectively imaged by using a contrast medium comprising a liposome containing said compound or a salt thereof.
Abstract(Chinese):

末端氟化烷基脂肪酸的类固醇酯化合物，具有双（三氟甲基）苯基的类固醇化合物，具有末端氟化烷基的磷脂酰丝氨酸化合物，具有双（三氟甲基苯基）或甘油酯化合物的甘油酯化合物或具有 通过使用包含含有所述化合物或其盐的脂质体的造影剂，可以选择性地成像血管损伤。

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