Invention Grant
- Patent Title: Cancer associated plexin B1 mutations
- Patent Title (中): 癌症相关性plexin B1突变
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Application No.: US10536804Application Date: 2003-11-28
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Publication No.: US07888007B2Publication Date: 2011-02-15
- Inventor: Magali Williamson , John Masters
- Applicant: Magali Williamson , John Masters
- Applicant Address: GB London
- Assignee: The Prostate Cancer Research Centre
- Current Assignee: The Prostate Cancer Research Centre
- Current Assignee Address: GB London
- Agency: Nixon & Vanderhye P.C.
- Priority: GB0227908.1 20021128
- International Application: PCT/GB03/05223 WO 20031128
- International Announcement: WO2004/050914 WO 20040617
- Main IPC: C12Q1/68
- IPC: C12Q1/68 ; G01N33/574 ; C07H21/02 ; C07H21/04
Abstract:
The present inventors have identified cancer associated mutations in plexinB1, which is a transmembrane receptor that mediates semaphorin signaling. The frequency of plexinB1 mutations, in particular in prostate and breast cancer, indicates that plexinB1 may be useful in the screening and diagnosis of cancer and as a drug target in the development of anti-cancer therapeutics.
Public/Granted literature
- US20060127908A1 Cancer associated plexinb1 mutations Public/Granted day:2006-06-15
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