Invention Grant
- Patent Title: P4HAS as modifiers of the IGFR pathway and methods of use
- Patent Title (中): P4HAS作为IGFR途径的修饰剂和使用方法
-
Application No.: US11628561Application Date: 2005-06-20
-
Publication No.: US07888048B2Publication Date: 2011-02-15
- Inventor: Lori S. Friedman , Helen Francis-Lang , Annette L. Parks , Kenneth James Shaw , Timothy S. Heuer , Lynn Margaret Bjerke
- Applicant: Lori S. Friedman , Helen Francis-Lang , Annette L. Parks , Kenneth James Shaw , Timothy S. Heuer , Lynn Margaret Bjerke
- Applicant Address: US CA South San Farncisco
- Assignee: Exelixis, Inc.
- Current Assignee: Exelixis, Inc.
- Current Assignee Address: US CA South San Farncisco
- Agency: McDonnell Boehnen Hulbert & Berghoff LLP
- International Application: PCT/US2005/021655 WO 20050620
- International Announcement: WO2006/009952 WO 20060126
- Main IPC: G01N33/53
- IPC: G01N33/53 ; G01N31/00
Abstract:
Human P4HA genes are identified as modulators of the IGFR pathway, and thus are therapeutic targets for disorders associated with defective IGFR function. Methods for identifying modulators of IGFR, comprising screening for agents that modulate the activity of P4HA are provided.
Public/Granted literature
- US20090025096A1 P4HAS AS MODIFIERS OF THE IGFR PATHWAY AND METHODS OF USE Public/Granted day:2009-01-22
Information query
IPC分类:
