Invention Grant
US07888061B2 Method of stabilising or reactivating a creatinine sensor with a divalent manganese ion
有权
用二价锰离子稳定或重新激活肌酸酐传感器的方法
- Patent Title: Method of stabilising or reactivating a creatinine sensor with a divalent manganese ion
- Patent Title (中): 用二价锰离子稳定或重新激活肌酸酐传感器的方法
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Application No.: US11434251Application Date: 2006-05-16
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Publication No.: US07888061B2Publication Date: 2011-02-15
- Inventor: Thomas Kjaer , Jens Østergaard , Tina Kristensen
- Applicant: Thomas Kjaer , Jens Østergaard , Tina Kristensen
- Applicant Address: DK Bronshoj
- Assignee: Radiometer Medical ApS
- Current Assignee: Radiometer Medical ApS
- Current Assignee Address: DK Bronshoj
- Agency: Morgan Lewis & Bockius LLP
- Main IPC: C12Q1/30
- IPC: C12Q1/30 ; C12Q1/26 ; C12M1/34

Abstract:
A method is provided for stabilizing a creatinine sensor comprising creatininase as a bioactive molecule. The creatininase is stabilised by exposing it to a sufficient amount of a divalent manganese ion. This result may be obtained by exposing the sensor to a solution comprising the divalent manganese ion or by introducing a composition within the sensor providing sustained release of the divalent manganese ion.
Public/Granted literature
- US20060275860A1 Method of stabilising or reactivating a creatinine sensor with a divalent manganese ion Public/Granted day:2006-12-07
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