Invention Grant
- Patent Title: Recombinant human factor IX and use thereof
- Patent Title (中): 重组人因子IX及其用途
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Application No.: US12624226Application Date: 2009-11-23
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Publication No.: US07888067B2Publication Date: 2011-02-15
- Inventor: Shu-Wha Lin , Chia-Ni Lin , Hua-Lin Wu , Guey-Yueh Shi
- Applicant: Shu-Wha Lin , Chia-Ni Lin , Hua-Lin Wu , Guey-Yueh Shi
- Applicant Address: TW Taipei
- Assignee: Shu-Wha Lin
- Current Assignee: Shu-Wha Lin
- Current Assignee Address: TW Taipei
- Agency: WPAT, P.C.
- Agent Anthony King
- Main IPC: C12P21/06
- IPC: C12P21/06
Abstract:
The present invention aims at converting factor IX into a molecule with enhanced activity which provides an alternative for replacement therapy and gene therapy for hemophilia B. Using recombinant techniques, factor IX with replacement at positions 86, 277, and 338 exhibits better clotting activity than recombinant wild type factor IX.
Public/Granted literature
- US20100081712A1 RECOMBINANT HUMAN FACTOR IX AND USE THEREOF Public/Granted day:2010-04-01
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