Host cells comprising alpha 1,2 mannosidase and culture methods thereof

Invention Grant

US07888101B2 Host cells comprising alpha 1,2 mannosidase and culture methods thereof 有权

Title translation: 包含α1,2甘露糖苷酶的宿主细胞及其培养方法

Patent Title: Host cells comprising alpha 1,2 mannosidase and culture methods thereof
Patent Title (中): 包含α1,2甘露糖苷酶的宿主细胞及其培养方法
Application No.: US11634757

Application Date: 2006-12-06
Publication No.: US07888101B2

Publication Date: 2011-02-15
Inventor: Christopher K. Crowell
Applicant: Christopher K. Crowell
Applicant Address: US CA Thousand Oaks
Assignee: Amgen Inc.
Current Assignee: Amgen Inc.
Current Assignee Address: US CA Thousand Oaks
Agent Michael G. Penn
Main IPC: C12P21/06
IPC: C12P21/06 ; C12N9/00 ; C12N9/26 ; C12N1/20 ; C12N15/00 ; C07K14/00 ; C07H21/04

Abstract:

Improved host cells and culture methods involving overexpression of MAN1C1 activity to improve protein production are provided.

Abstract(Chinese):

提供了改善的宿主细胞和培养方法，其涉及MAN1C1活性的过表达以改善蛋白质生产。

Public/Granted literature

Information query

Espacenet

IPC分类:

C	化学；冶金
C12	生物化学；啤酒；烈性酒；果汁酒；醋；微生物学；酶学；突变或遗传工程
C12P	发酵或使用酶的方法合成目标化合物或组合物或从外消旋混合物中分离旋光异构体
C12P21/00	肽或蛋白质的制备（单细胞蛋白质入C12N1/00）
C12P21/06	.由肽键水解产生，如水解产物