Invention Grant
- Patent Title: Phenylpyrazole derivatives
- Patent Title (中): 苯基吡唑衍生物
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Application No.: US12741754Application Date: 2008-11-13
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Publication No.: US07888354B2Publication Date: 2011-02-15
- Inventor: Toshio Nakamura , Makoto Tatsuzuki , Dai Nozawa , Tomoko Tamita , Seiji Masuda , Hiroshi Ohta , Shuhei Kashiwa , Aya Fujino , Shigeyuki Chaki , Toshiharu Shimazaki
- Applicant: Toshio Nakamura , Makoto Tatsuzuki , Dai Nozawa , Tomoko Tamita , Seiji Masuda , Hiroshi Ohta , Shuhei Kashiwa , Aya Fujino , Shigeyuki Chaki , Toshiharu Shimazaki
- Applicant Address: JP Tokyo
- Assignee: Taisho Pharmaceutical Co., Ltd
- Current Assignee: Taisho Pharmaceutical Co., Ltd
- Current Assignee Address: JP Tokyo
- Agency: Sughrue Mion, PLLC
- Priority: JP2007-294040 20071113; JP2008-153736 20080612
- International Application: PCT/JP2008/070712 WO 20081113
- International Announcement: WO2009/063953 WO 20090522
- Main IPC: A61K31/5377
- IPC: A61K31/5377 ; A61K31/397 ; A61K31/495 ; A61K31/4155 ; C07D413/14 ; C07D403/14 ; C07D205/02 ; C07D231/10

Abstract:
The present invention provides a prophylactic or therapeutic agent for dementia, Alzheimer's disease, attention-deficit hyperactivity disorder, schizophrenia, eating disorders, obesity, diabetes, hyperlipidemia, sleep disorders, narcolepsy, sleep apnea syndrome, circadian rhythm disorder, depression, allergic rhinitis or other diseases.A phenylpyrazole derivative represented by formula (1) or a pharmaceutically acceptable salt thereof: {wherein R1 and R2, which may be the same or different, each represent C1-C6 alkyl or C3-C8 cycloalkyl, or R1 and R2 are attached to each other together with their adjacent nitrogen atom to form a 4- to 7-membered saturated heterocyclic ring (wherein said saturated heterocyclic ring may be substituted with halogen or C1-C6 alkyl), n represents an integer of 0 to 2, T represents a hydrogen atom, halogen or C1-C6 alkyl, and R represents formula (I): or the like}.
Public/Granted literature
- US20100267687A1 PHENYLPYRAZOLE DERIVATIVES Public/Granted day:2010-10-21
Information query
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