中科微点-全球专利检索

  1. Login
  2. Sign Up
Invention Grant
US07888359B2 Cyclohexyl or piperidinyl carboxamide antibiotic derivatives 失效
环己基或哌啶甲酰胺抗生素衍生物

Cyclohexyl or piperidinyl carboxamide antibiotic derivatives
Abstract:
The invention relates to antibiotic cyclohexyl or piperidinyl carboximide derivatives of formula (I) wherein R1 represents hydrogen, halogen, (C1-C4)alkyl, (C1-C4)alkoxy, cyano or COOR2, R2 being (C1-C4)alkyl; one or two of U, V, W and X represent(s) N and the remaining represent each CH, or, in the case of X, may also represent CRX, RX being a halogen atom; either B represents N and A represents CH2CH2 or CH(OR3)CH2, or B represents CH or C(OR4) and A represents OCH2, CH2CH(OR5), CH(OR6)CH2, CH(OR7)CH(OR8), CH═CH or CH2CH2; each of R3, R4, R5, R6, R7, and R8 represents independently hydrogen, SO3H, PO3H2, CH2OPO3H2 or COR9, R9 being either CH2CH2COOH or such that R9—COOH is naturally occurring amino acid or dimethylaminoglycine; and to salts of such compounds of formula (I).
Abstract(Chinese):

本发明涉及式（I）的抗生素环己基或哌啶基甲酰亚胺衍生物，其中R1表示氢，卤素，（C1-C4）烷基，（C1-C4）烷氧基，氰基或COOR2，R2是（C1-C4）烷基; U，V，W和X中的一个或两个表示（s）N，其余表示每个CH，或者在X的情况下也可以表示CRX，RX表示卤素原子; B表示N，A表示CH 2 CH 2或CH（OR 3）CH 2，或B表示CH或C（OR 4），A表示OCH 2，CH 2 CH（OR 5），CH（OR 6）CH 2，CH（OR 7）CH（OR 8） = CH或CH2CH2; R 3，R 4，R 5，R 6，R 7和R 8各自独立地表示氢，SO 3 H，PO 3 H 2，CH 2 OPO 3 H 2或COR 9，R 9是CH 2 CH 2 COOH或使得R 9 -COOH是天然存在的氨基酸或二甲基氨基甘氨酸; 和式（I）化合物的盐。

Public/Granted literature
Information query
Espacenet
Patent Agency Ranking
0/0