Invention Grant
US07888394B2 Synthesis, polymorphs, and pharmaceutical formulation of FAAH inhibitors
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FAAH抑制剂的合成，多晶型物和药物制剂
- Patent Title: Synthesis, polymorphs, and pharmaceutical formulation of FAAH inhibitors
- Patent Title (中): FAAH抑制剂的合成，多晶型物和药物制剂
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Application No.: US11839746Application Date: 2007-08-16
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Publication No.: US07888394B2Publication Date: 2011-02-15
- Inventor: David Putman , Olivier Dasse
- Applicant: David Putman , Olivier Dasse
- Applicant Address: NL Oss
- Assignee: N.V. Organon
- Current Assignee: N.V. Organon
- Current Assignee Address: NL Oss
- Agent Maria V. Marucci; Valerie J. Camara
- Main IPC: A61K31/135
- IPC: A61K31/135 ; C07C209/00
Abstract:
Pharmacological inhibition of fatty acid amide hydrolase (FAAH) activity leads to increased levels of fatty acid amides. The alkylcarbamic acid aryl ester of Formula (I), KDS-4103, is a FAAH inhibitor. Described herein is a process for the preparation of the compound of Formula (I), characterization of polymorphs of the FAAH inhibitor, and their uses therof.
Public/Granted literature
- US20090030074A1 SYNTHESIS, POLYMORPHS, AND PHARMACEUTICAL FORMULATION OF FAAH INHIBITORS Public/Granted day:2009-01-29
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