Invention Grant
- Patent Title: Cytotoxic factors for modulating cell death
- Patent Title (中): 调节细胞死亡的细胞毒性因子
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Application No.: US11508173Application Date: 2006-08-23
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Publication No.: US07888468B2Publication Date: 2011-02-15
- Inventor: Ananda M. Chakrabarty , Tapas K. Das Gupta , Vasu Punj , Olga Zaborina , Yoshinori Hiraoka , Tohru Yamada
- Applicant: Ananda M. Chakrabarty , Tapas K. Das Gupta , Vasu Punj , Olga Zaborina , Yoshinori Hiraoka , Tohru Yamada
- Applicant Address: US IL Urbana
- Assignee: The Board of Trustees of the University of Illinois
- Current Assignee: The Board of Trustees of the University of Illinois
- Current Assignee Address: US IL Urbana
- Agency: Sheppard, Mullin, Richter & Hampton LLP
- Agent Don J. Pelto
- Main IPC: C07K5/00
- IPC: C07K5/00 ; A01N61/00 ; A61K38/00
Abstract:
Cytotoxic factors having use in modulating cell death, and their use in methods of treating necrosis or apoptosis-related conditions are disclosed. The invention also relates to methods for identifying active agents useful in treating conditions related to cell death or uncontrolled growth. The present inventors have found that different microorganisms produce different cytotoxic factor(s) having anticancer activity. The substantially pure cytotoxic factors can be used in a method of treating an infectious disease or a cancer.
Public/Granted literature
- US20060292136A1 Cytotoxic factors for modulating cell death Public/Granted day:2006-12-28
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