Invention Grant
- Patent Title: Post-translation modification and clostridial neurotoxins
- Patent Title (中): 翻译后修饰和梭菌神经毒素
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Application No.: US11624146Application Date: 2007-01-17
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Publication No.: US07888469B2Publication Date: 2011-02-15
- Inventor: Lance E. Steward , Ester Fernandez-Salas , Athena Spanoyannis , K. Roger Aoki , Wei-Jen Lin
- Applicant: Lance E. Steward , Ester Fernandez-Salas , Athena Spanoyannis , K. Roger Aoki , Wei-Jen Lin
- Applicant Address: US CA Irvine
- Assignee: Allergan, Inc.
- Current Assignee: Allergan, Inc.
- Current Assignee Address: US CA Irvine
- Agent Kenton Abel; Dean Stathakis; Debra Condino
- Main IPC: A61K39/00
- IPC: A61K39/00 ; C07K1/00

Abstract:
The present invention discloses modified neurotoxins with altered biological persistence. In one embodiment, the modified neurotoxins are derived from Clostridial botulinum toxins. Such modified neurotoxins may be employed in treating various conditions, including but not limited to muscular disorders, hyperhidrosis, and pain.
Public/Granted literature
- US20100273986A1 POST-TRANSLATIONAL MODIFICATION AND CLOSTRIDIAL NEUROTOXINS Public/Granted day:2010-10-28
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